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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPJ All Species: 13.03
Human Site: S872 Identified Species: 28.67
UniProt: Q9HC77 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HC77 NP_060921.3 1338 153000 S872 L M M K F F P S L K P K P K S
Chimpanzee Pan troglodytes Q5BQN8 1338 152866 S873 L M M K F F P S L K P K P K S
Rhesus Macaque Macaca mulatta XP_001117666 1300 147285 A839 L M M K F F P A L K P K P K S
Dog Lupus familis XP_543181 1355 154131 A880 L M M K F F P A L K L K P K A
Cat Felis silvestris
Mouse Mus musculus Q569L8 1344 153034 S864 L M V K F F P S L K P K P K L
Rat Rattus norvegicus NP_001100735 1307 147827 S823 L M V K F F P S L K P K P K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510637 1256 142839 P785 N L M M K L F P S L K P K K K
Chicken Gallus gallus XP_417152 1227 138809 F767 S N L M V K L F P S L K T K Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697409 1124 126471 R712 K Q E N Q D I R E N L K K D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649701 901 103264 K489 M E R V H D E K I Q A E I Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001201804 443 50264 E30 K D R T V A L E T E N T E L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 86.6 78.7 N.A. 73.5 69.5 N.A. 53 47.5 N.A. 34 N.A. 22.5 N.A. N.A. 20.7
Protein Similarity: 100 99.1 90.2 86.4 N.A. 82.6 79.1 N.A. 65.9 61.8 N.A. 50.5 N.A. 39 N.A. N.A. 27.7
P-Site Identity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. 13.3 13.3 N.A. 6.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 20 20 N.A. 6.6 N.A. 26.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 19 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 19 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 10 0 0 0 10 10 10 10 0 10 10 0 0 % E
% Phe: 0 0 0 0 55 55 10 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 0 10 0 0 % I
% Lys: 19 0 0 55 10 10 0 10 0 55 10 73 19 73 19 % K
% Leu: 55 10 10 0 0 10 19 0 55 10 28 0 0 10 28 % L
% Met: 10 55 46 19 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 0 0 0 0 0 10 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 55 10 10 0 46 10 55 0 0 % P
% Gln: 0 10 0 0 10 0 0 0 0 10 0 0 0 0 10 % Q
% Arg: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 10 % R
% Ser: 10 0 0 0 0 0 0 37 10 10 0 0 0 0 28 % S
% Thr: 0 0 0 10 0 0 0 0 10 0 0 10 10 0 0 % T
% Val: 0 0 19 10 19 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _